Comparison of Efficiency of Closed Kinetic Chain Exercises Versus Proprioceptive Exercises in Improving Balance and Gait in Patient With Hemophilia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- Medio-lateral and Anterior-posterior stability index
研究概览
简要总结
Hemophilia is a bleeding disorder caused by a deficiency of clotting factors in the blood. Muscle and joint bleeding are frequently observed in patients with hemophilia. Lower extremity bleeding can adversely affect balance, gait, and proprioception. The goal of this study; To compare the effectiveness of closed kinetic chain exercises and proprioceptive exercises on balance, proprioception and gait parameters in adolescent and young hemophilic individuals with lower extremity joint involvement.
The main question it aims to answer is:
Are the effects of closed kinetic chain exercises and proprioceptive exercises different on balance and walking in hemophilic individuals?
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 13 Years 至 25 Years（Child, Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Having been diagnosed with Hemophilia A and Hemophilia B
- •Having a blood factor level below 5%,
- •Between 13-25 years old
- •History of bleeding to the lower extremity and target joint
- •Total lower extremity Hemophilia joint health score ≥3
- •Using prophylaxis
排除标准
- •Having undergone lower extremity surgery in the last 6 months
- •Having a Body Mass Index over 30 kg/m2
- •Have an inhibitor
- •Using a walking aid
研究组 & 干预措施
Closed Chain Exercise Group
Closed kinetic chain exercises will be given under the supervision of a physiotherapist, 2 sessions a week for 12 weeks.
干预措施: Closed Chain Exercise Group (Other)
Proprioceptive Exercise Group
Proprioceptive exercises will be given under the supervision of a physiotherapist, 2 sessions a week for 12 weeks.
干预措施: Proprioceptive Exercise Group (Other)
Control Group
No intervention will be applied.
结局指标
主要结局
Medio-lateral and Anterior-posterior stability index
时间窗: 12 weeks
Represents fluctuations from the horizontal around the mediolateral axis. Mediolateral sway and anterior-posterior stability will record in the double-leg stance for 20 seconds with Biodex Balance System. The feet are placed in a comfortable position for patients, and the center of gravity was recorded in the system to begin the test. Each test will repeat 3 times. A higher sway index indicates a decrease in postural stability.
walking speed
时间窗: 12 weeks
A 10-meter walking test will be used to evaluate walking.
Hemophilia joint health score
时间窗: 12 weeks
The HJHS is derived from a physical examination of the index joints by a health care professional who should have training and expertise in the conduct of a detailed musculoskeletal (MSK) examination. It is a measure of joint health and sits within the World . The current HJHS version 2.1 comprises an assessment of specific features, or items, of the six index joints and an assessment of global gait. For each of the six joints, the following items are scored: swelling (scored 0-3), duration of swelling (0-1), muscle atrophy (0-2), crepitus on motion (0-2), flexion loss (0-3), extension loss (0-3), joint pain (0-2), and strength (0-4). The maximum score for an individual index joint is 20. Gait is scored 0 to 4. The maximum HJHS total score is 124, with a higher score indicating worse joint health.
次要结局
- 2-dimensional video-based gait kinematic analysis(12 weeks)
- Single leg stance test(12 weeks)
- Proprioception(12 weeks)
研究者
Tuğçe Poyraz İşleyen
Lecturer
Bahçeşehir University