TCTR20160902001已完成未知
The physiologic study of high-flow nasal oxygen cannula in patients with chronic obstructive pulmonary disease with acute exacerbation requiring ventilator support
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 40 Years 至 85 Years（—）
- 性别
- All
入选标准
- •1. Age 40-85 years old
- •2. Patients who was diagnosed COPD classified by GOLD criteria (post-bronchodilator FEV1/FVC < 70%)
- •3. Acute exacerbation of COPD with indication for NIV use as follows
- •- Acute respiratory acidosis (pH/=45 mmHg)
- •- Respiratory rate > 24 breaths/min
- •- Accessory muscles use or abdominal paradox breathing
排除标准
- •1. pH < 7.25
- •2. Severe hypoxemia
- •3. Alteration of consciousness and uncooperative (GCS < 8)
- •4. Hemodynamic instability or serious cardiac problem e.g hypotension, malignant arrhythmia, myocardial ischemia
- •5. Facial abnormality or recent facial/upper GI tract surgery
- •6. Uncontrolled airway or upper GI bleeding
- •7. Contraindication for insertion of esophageal balloon catheter - ulcer, varices, tumor, recent esophageal/gastric surgery, bleeding diathesis or allergy to lidocaine
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