Performance Enhancement and Non-Invasive Brain Stimulation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 121
- 试验地点
- 3
- 主要终点
- Change in ratings on cognitive training survey
研究概览
简要总结
A promising form of enhancing brain function non-invasively involves stimulating the brain using weak magnetic or electric currents. This method is becoming increasingly popular in both clinical and commercial circles; a number of portable, at-home devices are available on the commercial market for personal use. In this study, the investigators aim to determine factors associated with the enhancement of cognitive and motor learning following transcranial direct-current stimulation in healthy young adults. Understanding how participants respond to brain stimulation is critical to maximizing the effectiveness of stimulation and determining its potential as a performance-enhancing aid for mental tasks. Future developments of this study may also inform the capacity of brain stimulation to act as non-drug alternative to treatment for cognitive decline.
详细描述
This study involves a single session of anodal tDCS, applied over the motor cortex, while performing a task of motor dexterity. Pre and post stimulation evaluations will assess any effects of the stimulation on motor and cognitive performance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participants must be in good health,
- •between 18-35 years of age
- •with no prior history of neurological diseases such as multiple sclerosis, Parkinson's disease, stroke with paralysis.
排除标准
- •Participants with cardiac stimulators (pace-makers) and those with metal implants in the skull will be excluded.
- •Pregnant women will also be excluded.
- •Participants will be required to fill out a brief health questionnaire to ensure that they have no conditions that would prevent brain stimulation.
研究组 & 干预措施
Group 1
Non-invasive brain stimulation protocol expected to improve performance, with cognitively challenging game
干预措施: Transcranial Direct Current Stimulation (Device)
Group 1
Non-invasive brain stimulation protocol expected to improve performance, with cognitively challenging game
干预措施: Working Memory Training (Behavioral)
Group 2
Non-invasive brain stimulation protocol not expected to improve performance, with cognitively challenging game
干预措施: Transcranial Direct Current Stimulation (Device)
Group 2
Non-invasive brain stimulation protocol not expected to improve performance, with cognitively challenging game
干预措施: Working Memory Training (Behavioral)
结局指标
主要结局
Change in ratings on cognitive training survey
时间窗: Baseline, Post-test following 20-minute stimulation period
This survey aims to assess participant perceptions on brain stimulation, and includes a series of related questions, rated on a scale of 1-7.
Change in cognitive performance
时间窗: Baseline, Post-test following 20-minute stimulation period
We will measure changes in cognitive performance on neuropsychological tests.
Change in game performance
时间窗: Baseline, Post-test following 20-minute stimulation period
We will measure changes in performance on a cognitively-challenging game performed concurrently with the non-invasive brain stimulation.
Change in motor performance
时间窗: Baseline, Post-test following 20-minute stimulation period
We will measure changes in motor performance on the Grooved Pegboard task.
次要结局
未报告次要终点