Effect of Taking Probiotics, Synbiotics and Heat-inactivated Probiotics on Physical and Psychological Health and Cognitive Functions in Adults: A Blind, Randomised, Placebo-Controlled Study

Macquarie University0 个研究点目标入组 192 人开始时间: 2021年8月23日最近更新: 2022年8月9日

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•Not self-identified as using insulin, probiotics or prebiotics products, gastrointestinal drugs;
•Not receiving any treatment involving experimental drugs, antibiotics, pharmaceuticals;
•Without a current or past history of acute or chronic illness, for example, chronic kidney disease, lung disease, and chronic or acute inflammatory disease, hepatic diseases, thyroid diseases, renal diseases, severe intestinal disease, celiac disease, peptic ulcer, gastrointestinal illness, functional dyspepsia (Rome IV classification), diseases or operations affecting digestion, absorption, or defecation, immunodeficiency, bleeding disorder or coagulopathy, cardiovascular diseases, respiratory diseases, heart attack, stroke, diabetes;
•Without a diagnosis of mental retardation, medical conditions affecting brain or cognitive functioning;
•Without a current or past history of substance abuse or dependence (inc. alcohol, cigarette, marijuana, opiates), or intravenous drug use;
•Not pregnant and lactation or planning to become pregnant during the study period;
•Not being a shift worker;
•Not participating in an investigational drug trial or another study that would interfere with study objectives or confound the interpretation of the study results during last two months;
•Not regular ingestion of probiotics, prebiotics;
•Not taking a medication;
•Being proficient in English.

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