Respiratory Variations of the Diameter of Superior Vena Cava for Predicting Fluid Responsiveness After Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- diameter of vena cava superior
研究概览
简要总结
In a recent study (Vignon 2017), respiratory variations of the diameter of superior vena cava had a greater diagnostic accuracy than pulse pressure variations and inferior vena cava respiratory variations in 540 medical and surgical ICU patients. But this indicator has not been investigated yet in cardiac surgery. The investigator aim to study respiratory variations of superior vena cava for predicting fluid responsiveness after cardiac surgery.
In post-operative cardiac surgery patients with hemodynamic failure, the investigator will measure respiratory vena caval variations with TEE (Trans oesophageal echocardiography). Then, the investigator will evaluate fluid responsiveness after a fluid challenge (Trendelenburg).
A ROC curve will be constructed in order to assess the optimal sensitivity and specificity of this parameter.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hemodynamic instability with hypotension,
- •Low cardiac output or norepinephrine requirements in the first 6 post-operative hours.
排除标准
- •TEE (Trans oesophageal echocardiography) contra-indication
- •Trendelenburg contra-indication
结局指标
主要结局
diameter of vena cava superior
时间窗: at 6 post-operative hours
measured with trans oesophageal echocardiography
次要结局
- % of pulse pressure respiratory variations(at 6 post-operative hours)
- % of respiratory variations of maximal Doppler velocity in pulmonary artery(at 6 post-operative hours)
- % of respiratory variations of maximal Doppler velocity in left ventricular outflow tract(at 6 post-operative hours)