GLP-1's Influence on Intestinal Blood Flow
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 3
- 主要终点
- blood flow
研究概览
简要总结
to investigate the effect of the human incretin hormone GLP-1 on mesenteric blood flow and cardiac parameters
详细描述
to investigate the effect of the human incretin hormone GLP-1 on mesenteric blood flow and cardiac parameters, in healthy subjects, 4 arms, task force monitor
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy subjects
排除标准
- •medical conditions
研究组 & 干预措施
GLP-1
1,5 nmol/kg,GLP-1 sc injection
干预措施: 1,5 nmol/kg GLP-1 9-36amide, sc injection (Other)
GLP-1
1,5 nmol/kg,GLP-1 sc injection
干预措施: Exendin-4 ;10 ug,sc injection (Other)
Exendin-4
Exendin-4 ;10 ug,sc injection
干预措施: 1,5 nmol/kg GLP-1 9-36amide, sc injection (Other)
isotonic saline
2 ml of isotonic saline, sc injection
干预措施: 1,5 nmol/kg,GLP-1 sc injection (Other)
isotonic saline
2 ml of isotonic saline, sc injection
干预措施: 1,5 nmol/kg GLP-1 9-36amide, sc injection (Other)
isotonic saline
2 ml of isotonic saline, sc injection
干预措施: saline (Other)
GLP-1 9-36amide
1,5 nmol/kg GLP-1 9-36amide, sc injection
干预措施: 1,5 nmol/kg,GLP-1 sc injection (Other)
GLP-1 9-36amide
1,5 nmol/kg GLP-1 9-36amide, sc injection
干预措施: Exendin-4 ;10 ug,sc injection (Other)
Exendin-4
Exendin-4 ;10 ug,sc injection
干预措施: 1,5 nmol/kg,GLP-1 sc injection (Other)
结局指标
主要结局
blood flow
时间窗: with in 120 minutes
blood flow change measured by ultra sound
次要结局
未报告次要终点
研究者
lasse bremholm hansen
MD, ass. professor, ph.d
Zealand University Hospital