Insulin Resistance and Lipid Profile in Non-Obese Women With Prolactinoma Treated With Dopamine Agonists
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,004
- 试验地点
- 1
研究概览
简要总结
Prolactin is suggested to influence insulin resistance, but scarce data is available on the metabolic profile of patients with prolactinoma.
The purpose of the protocol was to evaluate cardiovascular disease risk factors in women with prolactinoma treated with dopamine agonists and to study the influence of disease control and anthropometry on their metabolic profile.
详细描述
A cross-sectional study was performed in non-obese premenopausal women with prolactinoma treated with dopamine agonists evaluated regarding glucose, insulin, Homeostasis Model Assessment (HOMA), lipid profile, C reactive protein (CRP), body mass index (BMI), waist circumference, prolactin, estradiol, testosterone, and sex hormone binding globulin (SHBG). They were compared with control women of similar age and BMI distribution.
研究设计
- 研究类型
- Observational
- 观察模型
- Defined Population
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 48 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Prolactinoma
- •Female gender
- •Premenopausal
排除标准
- •Obesity (BMI ≥ 30 kg/m²)
- •Diabetes mellitus
- •Hypertension
- •GH deficiency
- •Hypothyroidism
- •Primary hypogonadism
- •Adrenal insufficiency
- •Pituitary surgery