The Influence of Hip Replacement (Subtrochanteric Osteotomy vs. Non-osteotomy) on Lower Extremity Hemodynamics in Crowe IV Hip Dysplasia Patient
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 主要终点
- Hip Harris Score
研究概览
简要总结
Explore the influence of hip replacement on lower extremity hemodynamics in Crowe Ⅳ hip dysplasia patient.
详细描述
Changes of limb length after total hip replacement is common, especially for Crowe Ⅳ hip dysplasia patient. Such change potentially increases tension of vessel and influence lower extremity hemodynamics. Till now, little is known in this area.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Unilateral Crow IV hip dysplasia;
- •Bilateral Crow IV hip dysplasia without osteoarthritis on the other side
排除标准
- •Patients with serious medical disease;
- •Patients with lower extremity vascular disease;
- •Patients with severe mental illness.
研究组 & 干预措施
total hip replacement with subtrochanteral osteotomy
subtrochanteral osteotomy is applied during total hip replacement
干预措施: total hip replacement with subtrochanteral osteotomy (Procedure)
total hip replacement with no osteotomy
no osteotomy is applied during total hip replacement.
干预措施: total hip replacement with no osteotomy (Procedure)
结局指标
主要结局
Hip Harris Score
时间窗: preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery.
change of hip harris score scale from baseline(preoperative) to 1 year after surgery.
Radiographic Results
时间窗: 1 week, 12 weeks, 24 weeks and 1 year after the surgery.
change of Radiographic Results from 1 week after surger to 1 year after surgery
Lower Limb Arterial CT Angiography
时间窗: preoperative, 1 week, 12 weeks after the surgery.
change of vascular diameter and vascular cross-sectional from baseline(preoperative) to 1 year after surgery baseline(preoperative) to 12 weeks after surgery.
Blood Viscosity
时间窗: preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery.
change of blood viscosity from baseline(preoperative) to 1 year after surgery.
Vascular Ultrasound Examination
时间窗: preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery.
change of systolic peak velocity, end-diastolic velocity, pulsation index, resistance index and blood flow from baseline(preoperative) to 1 year after surgery.
Leg Length Change
时间窗: preoperative, 1 week, 6 weeks, 12 weeks, 24 weeks and 1 year after the surgery.
change of Leg Length from baseline(preoperative) to 1 year after surgery.
次要结局
未报告次要终点