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临床试验/NCT03964428
NCT03964428已完成不适用

Decreased Ferritin And Increased Hepcidin Serum Levels In Periodontitis Patients With Diabetes Mellitus Type 2. Controlled Before-And-After Study

Fayoum University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2018年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
1
主要终点
ferritin concentration

研究概览

简要总结

serum level of ferritin and hepicidin were evaluated in periodontitis patient with and without type 2 diabetes before and after non surgical periodontal treatment to clarify their in periodontal disease

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
30 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm with T2DM
  • systemically healthy patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm
  • healthy subjects had clinically healthy gingiva with ≤ 3mm pocket probing depth (PPD), nearly zero plaque index (PI), gingival index (GI), zero CAL.

排除标准

  • (I) Pregnancy or lactation, (II) History of receiving professional periodontal treatment during the past 6 months; (III) Treatment with any type of medications and/ or antibiotics during the past 3 months and (IV) Current or former smokers.

结局指标

主要结局

ferritin concentration

时间窗: 0-3 months

ng/ml

hepicidin concentration

时间窗: 0-3 months

ng/ml

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nayroz Abdel Fattah Mohamed Tarrad

lecturer

Fayoum University

研究点 (1)

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