Use of Diced Cartilage for Management of Internal Mammary Vessel Exposure Sites in Autologous Breast Reconstruction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 173
- 试验地点
- 2
- 主要终点
- Magnetic resonance imaging (MRI) scans: soft tissue sinking of the recipient vessels area
研究概览
简要总结
Exposure of internal mammary vessels in autologous breast reconstruction often requires removal of a rib cartilage segment, which can lead to contour deformity in the craniomedial breast pole. This study evaluated the use of diced cartilage (DC) to counteract substance loss in the microvascular anastomosis area, and investigated safety and suitability of the procedure to avoid postoperative deformities.
详细描述
This retrospective, single-center cohort study included all breast reconstructions in which DC was used from October 2021 to June 2023. Reconstructions using DC were subdivided based on previous exposure to breast radiotherapy (DC vs. DCR). The control group consisted of an equal number of consecutive reconstructions performed prior to the use of DC. The effect of DC on breast contour preservation was investigated using breast magnetic resonance imaging (MRI; > 6 months post-op) and photographic documentation (6-month follow-up).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Autologous free flap breast reconstruction using the internal mammary vessels as recipient vessels from October 2021 to June 2023
- •MRI subcohort: Magnetic resonance imaging (MRI) scans performed at least 6 months postoperatively
排除标准
- •Autologous free flap breast reconstruction using a perforator of the internal mammary vessels as recipient vessels from October 2021 to June 2023
- •Autologous free flap breast reconstruction using the thoracodorsal vessels as recipient vessels from October 2021 to June 2023
结局指标
主要结局
Magnetic resonance imaging (MRI) scans: soft tissue sinking of the recipient vessels area
时间窗: October 2021 to June 2023
the sinking depth of epicostal soft tissue into the space of rib segment resection on axial planes in Magnetic resonance imaging (MRI) scans performed at least 6 months postoperatively
次要结局
- Visual contour deficit of the recipient vessels area(October 2021 to June 2023)
研究者
Peter Paul Pfeiler, MD
Consultant
ISAR Klinikum