Analysis of Inflammation in the Vitiligo and Other Inflammatory Skin Diseases: Psoriasis, Atopic Dermatitis and Alopecia Areata
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 450
- 试验地点
- 2
- 主要终点
- Description of the phenotype and function of blood and skin T-cell in chronic inflammatory skin disorders: psoriasis, vitiligo, atopic dermatitis, alopecia areata
研究概览
简要总结
It is a study of translational research with mechanistically objectives and including biological samples of patients with chronic inflammatory disorders
详细描述
This study was a single-center prospective study to collect blood and skin tissue at the time of consultation with a patient with non-segmental vitiligo, psoriasis, atopic dermatitis or alopecia areata, in order to better understand and compare blood and skin immune response in chronic inflammatory skin disorders: psoriasis, alopecia areata, atopic dermatitis and vitiligo.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 to 75 years;
- •Patients with non-segmental vitiligo;
- •Patients with plaque psoriasis;
- •Patients with atopic dermatitis;
- •Patients with alopecia areata sclerosis;
- •written consent, free, informed and signed by the patient and the investigator (before any examination required by the study);
- •Subject affiliated or beneficiary of a social security system.
排除标准
- •Patients with segmental vitiligo
- •Patients under local treatment (topical corticosteroid-Calcineurin inhibitor) for less than two weeks.
- •Patients on therapy, systemic treatments: acitretin, methotrexate, cyclosporine, Apremilast, infliximab, adalimumab, etanercept, ustekinumab, secukinumab, ixekizumab, dupilumab) for less than 4 weeks.
- •Pregnant or breastfeeding women
- •Patient (e) under guardianship
- •Patient (e) Non-affiliated (e) a social protection
结局指标
主要结局
Description of the phenotype and function of blood and skin T-cell in chronic inflammatory skin disorders: psoriasis, vitiligo, atopic dermatitis, alopecia areata
时间窗: Day 1
Description of the phenotypic analysis of cutaneous T-cell and blood of vitiligo patients evaluated by flow cytometry
次要结局
未报告次要终点