Effects of Acute and Prolonged Caffeine Intake on Neuromuscular Adaptations to Resistance Training in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 48
- 试验地点
- 2
- 主要终点
- Mean velocity at different %1RM
研究概览
简要总结
Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, little is known about the prolonged effects of this supplement on neuromuscular adaptations to strength training.
Objectives: The present study aims to analyze the effects of acute and chronic caffeine intake on neuromuscular adaptations to strength training, according to sex (men vs. women) and type of exercise (bench press vs. squat), as well as fatigue perception, mood state, and potential side effects in older adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age between ≥ 55
- •Body mass index (BMI) ≥ 30 kg/m².
- •Physically active subjects (>150 min/week of moderate exercise).
- •Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from performing physical exercise.
- •Participants capable of performing the tests.
排除标准
- •History of neuromuscular, cardiac, or diseases that could affect liver or muscle metabolism.
- •Use of drugs or other stimulants that interfere with caffeine intake and intestinal absorption during the tests and study.
- •Having undergone prolonged periods of forced physical inactivity during the 6 months prior to the study.
- •Performing strenuous exercise within 48 hours prior to the tests.
- •Failing to replicate the same food intake on the two experimental days.
- •Consuming caffeine after 6 PM on the day prior to training or testing.
研究组 & 干预措施
Caffeine - Females
干预措施: Caffeine + Resistance exercise (Dietary Supplement)
Placebo - Females
干预措施: Placebo + Resistance exercise (Dietary Supplement)
Caffeine - Males
干预措施: Caffeine + Resistance exercise (Dietary Supplement)
Placebo - Males
干预措施: Placebo + Resistance exercise (Dietary Supplement)
结局指标
主要结局
Mean velocity at different %1RM
时间窗: Through study completion, an average of 12 weeks
Measuring bar mean velocity desplacement during bench press and back squat exercises.
Peak velocity at different %1RM
时间窗: Through study completion, an average of 12 weeks
Measuring bar peak velocity and time to reach peak velocity of bar desplacement during bench press and back squat exercises.
Mean power output at different %1RM
时间窗: Through study completion, an average of 12 weeks
Measuring during bench press and back squat exercises.
Peak power output and time to reach peak power output at different %1RM
时间窗: Through study completion, an average of 12 weeks
Measuring during bench press and back squat exercises.
Number of repetitions performed at 65%1RM until task failure
时间窗: Through study completion, an average of 12 weeks
In bench press and back squat exercises
Bar velocity deplacement performed in 1 set at 65%1RM until task failure
时间窗: Through study completion, an average of 12 weeks
In bench press and back squat exercises
Power output generated in 1 set at 65%1RM until task failure
时间窗: Through study completion, an average of 12 weeks
In bench press and back squat exercise
Resting Metabolic Rate (RMR)
时间窗: Through study completion, an average of 12 weeks
Kcal at rest (RMR) using a metabolic chart.
Maximal Fat Oxidation Rate (MFO)
时间窗: Through study completion, an average of 12 weeks
g/min (MFO) using a metabolic chart.
次要结局
- Fat mass(Through study completion, an average of 12 weeks)
- Fat-free mass(Through study completion, an average of 12 weeks)
- Physical activity (METs-min/wk)(Through study completion, an average of 12 weeks)
- Dietary (g/kg of macronutrients)(Through study completion, an average of 12 weeks)
- Mood state(Through study completion, an average of 12 weeks)
- Adverse effects(Through study completion, an average of 12 weeks)
研究者
Alberto Pérez-López
Principal Investigator
University of Alcala