Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 63
- 试验地点
- 1
- 主要终点
- Postoperative complications
研究概览
简要总结
Malnutrition is common in patients with lung cancer. In patients with malnutrition risk, the risk of complications is high both in the perioperative, early and late postoperative periods. Malnutrition is an independent risk factor for length of hospital stay and cost in these patients. Patients with lung cancer may have many morbidities in postoperative period, especially problems with wound healing. Therefore, assessment of the nutritional status of patients with lung cancer should begin at the diagnosis stage.
详细描述
In patients with lung cancer scheduled for lobectomy, anthropometric measurements will be measured and the results of laboratory tests(albumin, prealbumin, creatinine, total lymphocyte count, C reactive protein), Nutritional Risk Screening-2002, Nutritional Risk Index, Mini Nutritional Assessment, Glasgow Prognostic Score, Prognostic Nutritional Index and neoadjuvant chemotherapy or not will be recorded in 72 hours before surgery. In addition, demographic information of the patients (name, surname, identification number, age, comorbidity, American Society of Anesthesiologists score) will be recorded. After the information is given to the patients, their written and verbal consent will be obtained.
In the operating room, routine monitoring (electrocardiography, invasive blood pressure measurement, arterial blood gas monitoring, peripheral oxygen saturation, end-tidal carbon dioxide measurement by capnography) will be applied to the patients in accordance with the standard protocol for elective lobectomy surgery.
Hemodynamic changes (eg. dysrhythmia, hypotension, hypertension, hemorrhage), metabolic status (pH, bicarbonate, base excess), lactate, glucose level in blood gas evaluation and intraoperative complications will be recorded during the intraoperative period.
In the postoperative period, length of stay in the intensive care unit, length of hospital stay, early complications (eg. dysrhythmia, acute coronary syndrome, sepsis, mediastinitis, pneumonia, surgical site infection, prolonged air leak), time to start oral intake and transition to adequate oral intake will be recorded in the one-month postoperative period.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Having a diagnosis of lung cancer
- •Lung lobectomy operation will be performed
- •18 years and older patients
- •Having an American Society of Anesthesiologists score of 1, 2, 3
- •Having approved and signed the informed consent form
排除标准
- •Patients who underwent lobectomy with a diagnosis other than lung cancer
- •Patients younger than 18 years
- •Patients with an American Society of Anesthesiologists score of 4 and above
- •Patients who did not accept informed consent
- •Patients who refused to participate in the study
结局指标
主要结局
Postoperative complications
时间窗: a month after the surgery
dysrhythmia, acute coronary syndrome, sepsis, mediastinitis, pneumonia, surgical site infection, prolonged air leak
Length of stay in the intensive care unit
时间窗: up to 30 days
Length of stay in the intensive care unit
Length of hospital stay
时间窗: up to 30 days
Length of hospital stay
Intraoperative hemodynamic complications
时间窗: during the procedure
dysrhythmia, hypotension, hypertension, hemorrhage
次要结局
- glucose(during the procedure)
- Oral intake(up to 30 days)
- bicarbonate(during the procedure)
- pH(during the procedure)
- base excess(during the procedure)
- lactate(during the procedure)