The Clinical Manifestations of SARS-Cov-2 Disease; Not Only Pulmonary
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 445
- 试验地点
- 1
- 主要终点
- Number of participants who has one or more of the following extrapulmonary clinical manifestations of SARS-CoV-2 .
研究概览
简要总结
A prospective observational study to identify different extrapulmonary clinical manifestations of SARS-CoV-2 and its correlations with the disease severity grades.
详细描述
The current research in this area was retrospective trials; this study is a prospective one. Investigators will perform the extensive recording of extrapulmonary manifestations in adult patients of SARS-CoV-2 and their correlations with the disease severity grades.
Type of the study: a prospective observational study
Study Setting:
Data will be collected from outpatients and inpatients files and a questionnaire.
Sample Size Calculation:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients have been confirmed diagnosed with Covid-19 disease by PCR
- •Patients aged 18 years and above
排除标准
- •Patients aged below 18 years old.
结局指标
主要结局
Number of participants who has one or more of the following extrapulmonary clinical manifestations of SARS-CoV-2 .
时间窗: one year
Cardiovascular : * Coronary Artery Disease * Infarction (type 2) * Myocarditis * Arrhythmia * Cardiogenic shock * Heart failure Gastrointestinal : * Anorexia * Diarrhea * Bleeding * Digestive symptoms * Abnormal liver tests Neurological : * Headache * Impaired consciousness * acute ischemic stroke * Ataxia * Dizziness * Seizure * Taste impairment * Smell impairment * Vision impairment * Viral encephalitis * Depression Endocrinal: * Hypoglycemia * Ketoacidosis * Hyperglycemia * Thyrotoxicosis * Secondary Adrenal Insufficiency Hematological: * Leukocytosis * Leukopenia * Thrombocytopenia * Anemia * Lymphocytosis * D-dimer * Lactate dehydrogenase * Ferritin Renal : * Albuminuria * Hematuria * Blood urea nitrogen * Acute kidney injury Ophthalmologic : -Conjunctivitis Dermatologic : * Papulovesicular rash * Rosacea * Dryness * Erythema * Urticaria * Maculopapular exanthem morbilliform
次要结局
- The correlations between the number of participants who has extrapulmonary manifestations and the severity grade of SARS-CoV-2.(one year)
研究者
Emad eldin arafa Aly
Allergist and Immunologist
Assiut University