EUCTR2011-001132-30-CZ进行中（未招募）1 期
on-invasive parameters in the evaluation of portal hypertension in patients with liver cirrhosis and their significance for the evolution of cardial complications.
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Liver cirrhosis with portal hypertension and esophageal varices
- •Indication for treatment with betablockers in the prevention of variceal bleeding
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 100
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Hepatocellular carcinoma
- •Advanced liver failure (Child-Pugh more than 13 points)
- •Contraindication to carvedilol:
- •Decompensated hearth failureNYHA IV
- •Known sensitivity to carvedilol or vehicules
- •Astma bronchiale
- •A-V block 2-3. degree
- •Severe bradycardie (under 50 beats/min)
- •Cardiogenic shock
- •Sick-sinus syndrom
- •Severe hypotension (systolic BP under 85 mm Hg)
- •Portosystemic shunt
- •Portal vein thrombosis
- •Gravidity or lactation
- •Age under 18 years
研究者
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