A Working Memory Training to Decrease Rumination in Depressed and Anxious Individuals: A Double-blind Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 98
- 试验地点
- 1
- 主要终点
- Change in Ruminative Response Scale (RRS) score from pre to post training and after two months (follow up 2)
研究概览
简要总结
Dysfunctioning executive functioning, including working memory (WM), is related to rumination. Findings show that working memory capacity (WMC) can be increased by training. The current study explored by means of a double-blind randomized controlled trial whether an adaptive WM training could reduce rumination, anxiety and depression in a sample of 98 depressed and anxious individuals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 67 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Major depression diagnosis
- •Anxiety diagnosis
排除标准
- •Current psychosis
- •Substance abuse
研究组 & 干预措施
Placebo working memory training
干预措施: Placebo training (Behavioral)
Working memory training
干预措施: Working memory training (Behavioral)
结局指标
主要结局
Change in Ruminative Response Scale (RRS) score from pre to post training and after two months (follow up 2)
时间窗: Pre training (baseline), post training (4 weeks after baseline, training starts 1 day after baseline) and follow-up (2 months after post-test)
Dutch version; Raes, Hermans, \& Eelen, 2003) measures the frequency of self-reported rumination behavior, with answer options ranging from 1 (never) to 4 (always). The total score of the 22 items was used in the analyses.
次要结局
- Change in Beck Depression Inventory Second Edition (BDI-II) score from pre to post training and after two months (follow up 2)(Pre training (baseline), post training (4 weeks after baseline, training starts 1 day after baseline) and follow-up (2 months after post-test))
- Change in State-Trait Anxiety Inventory (STAI) score from pre to post training and after two months (follow up 2)(Pre training (baseline), post training (4 weeks after baseline, training starts 1 day after baseline) and follow-up (2 months after post-test))
研究者
Ingmar Franken
Professor
Erasmus Medical Center