Blood Loss at the Time of First Trimester Surgical Abortion in Anticoagulated Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Volume of Intraoperative Blood Loss
研究概览
简要总结
The primary objective of this study is to compare blood loss resulting from surgical termination of pregnancy up to 12 weeks gestation between women who are anticoagulated to therapeutic levels and those who are not anticoagulated. This study is based on the hypothesis that anticoagulant therapy does not increase intraoperative blood loss in women receiving surgical abortions up to 12 weeks gestation.
详细描述
We intend to conduct a prospective cohort study at Oregon Health and Science University and the University of Hawaii. This study will not be blinded and subjects will not be randomized. Women will be approached about this study after they have made a decision to terminate the pregnancy and have completed the preoperative history and physical examination and surgical consenting process. For patients who are receiving anticoagulant medications, the decision to continue anticoagulant therapy or interrupt it will be made by the patient's physician, independently of this study.
We will recruit women who continue on anticoagulant therapy (heparin, low molecular weight heparin, or warfarin) without interruption for the surgical procedure. Our control group will consist of women who are not on anticoagulant treatment. This is a matched study and our control group will be matched for gestational age, parity, and cesarean section history.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female seeking abortion services
- •Less than or equal to 12 weeks gestation
- •Age 18-50
- •Willing and able to sign informed consent
- •Use of Coumadin or LMW heparin (treatment group only)
排除标准
- •Unwilling or unable to sign informed consent
- •Women taking daily aspirin or herbal therapies containing gingko biloba
- •Women with a known history of a bleeding disorder such as von willebrand's disease
结局指标
主要结局
Volume of Intraoperative Blood Loss
时间窗: Post procedure
Quantitative blood loss using volume measurement and weight
次要结局
未报告次要终点
研究者
Bliss Kaneshiro
Associate Professor
University of Hawaii
