Preclinical Development of a Speech-based Digital Biomarker for Psychiatric Disease
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Speech recordings
研究概览
简要总结
The general objectives of this study are to build a proof-of-concept, speech-based, digital biomarker for identifying the presence and tracking the severity of psychiatric disease.
详细描述
The purpose of this study is to gather longitudinal data to examine how speech features and symptoms change over different intervals of time and the reliability of repeated, high frequency test administration. Participants will complete a variety of speech and language tasks using the Winterlight Assessment (iOS app) everyday for 30 days. The following is the list of assessments that participants will complete; 1) Daily assessment of mood, 2) Winterlight assessment which contains a series of verbal response tasks where participants are recorded through a tablet app, and 3) Clinical assessments.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male and Female adults aged 18 to
- •English as a first language, or English as a second language with conversational proficiency.
- •Own an iOS device (iPhone or iPad) and willing to install the study app.
- •A reliable (cellular or WiFi) home internet connection and accessible email address
排除标准
- •Residence outside of Canada or the United States.
- •Clinically significant vision impairment (corrected vision is acceptable).
- •Clinically significant hearing impairment (use of hearing aids is acceptable)
结局指标
主要结局
Speech recordings
时间窗: Everyday for 30 business days until study completion, about 2 years
500+ features to be extracted from each recording
次要结局
- Depression scores(Everyday for 30 business days until study completion, about 2 years)