Early Mobilization of Ischemic Stroke Patients Within 24-hours After Intravenous-tPA Infusion.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Level of Patient Disability post-TPA Infusion.
研究概览
简要总结
The purpose of this study is to study the safety and feasibility of mobilization of acute ischemic stroke patients treated with IV-tPA between 12-24 hours of treatment.
详细描述
Abstract:
Introduction
Historical precedence exists demonstrating that early intensive care unit (ICU) mobilization of patients reduces risks of complication and lengths of hospital stay, and may improve long-term health status of patients.
Objective
To determine the safety of early mobilization by physical and/or occupational therapy in acute ischemic stroke patients within 24-hours of IV-tPA infusion and to examine if early mobilization leads to shortened ICU and hospital length of stay.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients post acute ischemic stroke that have been treated with intravenous tissue plasminogen activator (IV-tPA)
- •13 hours have elapsed since initiation of intravenous TPA infusion
- •Patients are hemodynamically stable (e.g., not on vasopressors or antihypertensive drips or requiring multiple IV PRN boluses of either medication)
- •Patient is able to actively engage in the evaluation
排除标准
- •Patients with femoral sheaths or recent removal of femoral sheaths
- •Patients who are hemodynamically unstable, with active bleeding from lines, catheters, INT site or wounds or angioedema
- •Electrocardiogram showing (HR>100)
- •Vital signs (HR > 100, SBP <90 or >180, DBP <70 or > 105)
- •Patients experiencing marked diaphoresis, facial pallor, intense anxious or painful facial expression (especially in aphasic patients)
结局指标
主要结局
Level of Patient Disability post-TPA Infusion.
时间窗: 30-days post-IV tPA infusion
Study participants will be contacted at approximately 3 to 5-days and 30-days post-IV tPA infusion to capture level of disability by use of Modified Rankin Scale.
次要结局
未报告次要终点