JPRN-UMIN000004826已完成2 期
Randomized crossover trial of Granisetron/Dexamethasone/Aprepitant versus Palonosetron/Dexamethasone/Aprepitant for the prevention of nausea and vomiting in patients receiving receiving Cisplatin containing chemotherapy for head and neck cancer - Randomized crossover trial of Granisetron/Dexamethasone/Aprepitant versus Palonosetron/Dexamethasone/Aprepitant for the prevention of nausea and vomiting in patients receiving receiving Cisplatin containing chemotherapy for head and neck cancer
Yokohama City University Graduate School of Medicine0 个研究点目标入组 60 人开始时间: 2011年1月6日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 75years-old(—)
- 性别
- All
入选标准
- 未提供
排除标准
- •1) with seizure disorder needing anticonvulsants unless clinically stable 2) with vomiting, retching, or grade 2 or higher nausea according to CTCAE 3) with QTc prolongation by electrocardiography (QTc: >470 msec) 4) with severe allergy to Palonosetron, Granisetron, Aprepitant and Dexamethasone 5) pregnant or nursing women or women who like be pregnant and men with partner willing to get pregnant 6) receiving an antiemetic drug 7) receiving pimozide (orap) 8) with history of mental disorder or treating it at the moment 9) doctor's decision not to be registered to this study
研究者
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