Glycemic and Satiety Response to Meals With Different Fiber Content and Glycemic Index in Type 2 Diabetic Patients
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- glycemic control
研究概览
简要总结
The aim of this study is to assess the post-prandial response of four breakfast with different content of dietary fiber and glycemic index on glycemic response and satiety in patients with type 2 diabetes.
详细描述
Design study:
Single-blind crossover randomized clinical trial
Hypothesis:
A meal with high GI and high fiber content determines a lower glycemic response compared to a meal with high GI and low fiber content (fiber beneficial effect on glycemic response independent of glycemic index.
Test meals:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •type 2 diabetes,
- •HbA1c < 9%,
- •BMI < 35kg/m²,
- •Metformin and/or diet as treatment for diabetes
排除标准
- •Use of insulin as diabetes treatment
- •digestive disease with malabsorption
- •diabetes neuropathy with gastroparesis
研究组 & 干预措施
meal D
low fiber and low GI
干预措施: GI and fiber meals (Other)
meal D
low fiber and low GI
干预措施: meals (Other)
meal C
low Fiber and High GI
干预措施: GI and fiber meals (Other)
meal C
low Fiber and High GI
干预措施: meals (Other)
meal B
high Fiber and low GI
干预措施: GI and fiber meals (Other)
meal B
high Fiber and low GI
干预措施: meals (Other)
meal A
high fiber and high GI meal
干预措施: GI and fiber meals (Other)
meal A
high fiber and high GI meal
干预措施: meals (Other)
结局指标
主要结局
glycemic control
时间窗: fasting and post-prandial (differents times during 180 minutes)
glucose and insulin
次要结局
- measures of satiety and appetite(fasting and post-prandial (different times for 180 min))