NCT06899620已完成不适用
Weizmannia Coagulans BC179 Alleviates Post-Alcohol Discomfort May Via Taurine-Related Metabolism and Antioxidant Regulation: A Randomized, Double-Blind，Placebo-Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Effects of BC179 on alcohol metabolism
研究概览
简要总结
To assess the effectiveness and safety of probiotic strain BC179 in reducing alcohol absorption in the gut, thereby lowering health risks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Inclusion Criteria:
- •Participants must be aged between 18 and 65 years.
- •They should have a documented history of long-term alcohol consumption, defined as consuming at least 20 grams of ethanol per day for at least one year. This is calculated using the formula: volume (mL) × alcohol content (%) × 0.
- •They must provide written informed consent and be willing to comply with the study procedures.
排除标准
- •History of chronic liver, gastrointestinal, or systemic metabolic disorders.
- •Use of products with similar functions to the investigational formulation within the past two weeks.
- •Use of antibiotics, laxatives, or dietary supplements within the past four weeks.
- •Documented history of hypertension or diabetes.
- •Severe allergies or immune deficiencies.
- •Pregnancy, lactation, or planning pregnancy without effective contraception during the study period.
结局指标
主要结局
Effects of BC179 on alcohol metabolism
时间窗: 60 days
The impact of BC179 on alcohol metabolism is assessed by monitoring blood alcohol concentration (BAC) and related enzyme activities, such as alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH).
次要结局
未报告次要终点
研究者
研究点 (2)
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