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临床试验/NCT00374764
NCT00374764已完成不适用

Randomized Double Blind Comparison of Applied Behavioral Analysis Versus ABA and Risperidone

Washington University School of Medicine1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2000年7月1日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
1

研究概览

简要总结

Hypotheses:

  1. Preschool children with autism spectrum disorders (ASDs) who undergo ABA treatment only will demonstrate significantly better outcomes compared to an age and severity matched control group without ABA treatment.
  2. Preschool children with ASDs who undergo ABA in combination with risperidone will demonstrate significantly better outcomes compared to age and severity matched children who are receiving ABA alone.
  3. Young age, cognitive development and attentional abilities at baseline will be predictive of good socio-emotional and neuropsychological outcomes after ABA treatment.
  4. At baseline, children with ASDs will show significantly lower performances on measures of cognitive, neuropsychological, and socio-emotional functioning than age-matched typically developing controls.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double

入排标准

年龄范围
30 Months 至 5 Years(Child)
性别
All
接受健康志愿者
是

入选标准

  • •Diagnosis of autism or severe pervasive developmental disorder (PDD) not otherwise specified (NOS) according to the Autism Diagnosis Interview-Revised (ADI-R)
  • •Aged 2.6 to 5.0.

排除标准

  • •Fragile X or metabolic etiology of PDD symptoms
  • •Diagnosis of other central nervous system (CNS) disorders
  • •Chronic serious medical problems

研究者

申办方类型
Other

研究点 (1)

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