Caffeine Increases Maximal Fat Oxidation During Exercise in Endurance-trained Men: is There a Diurnal Variation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- MFO
研究概览
简要总结
Maximal fat oxidation during exercise (MFO) and the intensity of exercise that elicits MFO (Fatmax) has been recognized as potential determinants of endurance performance.
The purpose of this study was to determine the possible interaction between the effects of diurnal variation (morning vs. afternoon) and caffeine ingestion on MFO, Fatmax and VO2 max in endurance-trained men. Specifically, the investigators sought to elucidate whether the stimulant actions of caffeine could reverse the decrements of MFO and Fatmax observed in the morning.
详细描述
Body weight, height, body composition (DXA), exercise test (MFO and VO2max assessment) will be measured during the 4 evaluations.
Participants were randomized into 4 exercise test conditions:
- Exercise test in the morning with placebo intake
- Exercise test in the evening with placebo intake
- Exercise test in the morning with caffeine intake
- Execrise test in the evening with caffeine intake
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Having a body mass index (BMI) ranged from 18.5 to 28 kg/m2
- •not suffering any specific disease which can be aggravated by physical exercise
- •having previous experience in endurance training (i.e. self-reporting at least 2 years of cycling or running training including more than 3 training sessions/week).
- •Participant must be capable and willing to provide consent, understand
排除标准
- •, instructions and protocols.
- •Exclusion Criteria:
- •Being smoker
- •Taking medication or drugs
- •Any non-controlled medical condition which could influence results or could be worsened by the participation in the study
- •Are deemed unsuitable by the investigator for any other reason, that prevent data collection.
研究组 & 干预措施
Caffeine
A dose of 3 mg/kg of caffeine (i.e. a vegetable extraction from green coffee beans, Harrison Sport Nutrition®, Spain) was ingested before the beginning of each test.
干预措施: Test in the morning (Behavioral)
Caffeine
A dose of 3 mg/kg of caffeine (i.e. a vegetable extraction from green coffee beans, Harrison Sport Nutrition®, Spain) was ingested before the beginning of each test.
干预措施: Test in the afternoon (Behavioral)
Placebo
A dose of 3 mg/kg of placebo (i.e. 100% purity microcrystalline cellulose, Acofarma, Spain) was ingested before the beginning of each test.
干预措施: Test in the morning (Behavioral)
Placebo
A dose of 3 mg/kg of placebo (i.e. 100% purity microcrystalline cellulose, Acofarma, Spain) was ingested before the beginning of each test.
干预措施: Test in the afternoon (Behavioral)
结局指标
主要结局
MFO
时间窗: Through study completion, an average of 1 month
Maximal fat oxidation during exercise
次要结局
- FATmax(Through study completion, an average of 1 month)
- VO2max(Through study completion, an average of 1 month)
研究者
Jonatan Ruiz Ruiz
Associate professor
Universidad de Granada