Ventricular tachyarrhythmia detection by Implantable Loop Recording in Patients with Heart Failure and Preserved Ejection Fraction - VIP-HF Registry

niversitair Medisch Centrum Groningen0 个研究点目标入组 250 人开始时间: 待定最近更新: 2024年4月29日

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•Clinical criteria:
•1. Age >18 years
•2. Written informed consent
•3. HF with moderate to severe symptoms NYHA II or III
•4. Hospitalization or emergency room visit for HF or symptom relief with diuretics within 12 months
•5. Sinus rhythm or AF with adequate rate control (exercise test: maximum heart rate <160 bpm) ;Echocardiographic criteria:
•1. LVEF >40%
•2. Left atrial size (volume *34 mL/m2 or LA parasternal diameter *45 or left ventricular hypertrophy (septal thickness or posterior wall thickness *11 mm) of left ventricular diastolic dysfunction (E/e* *13 or mean e* septal and lateral wall <9 cm/s).;Biomarker criteria:
•1. BNP >75ng/L or NT-pro-BNP>300ng/L if sinus rhythm
•2. BNP >225ng/L or NT-pro-BNP>900ng/L if atrial fibrillation

•1. Patients unwilling or unable to sign informed consent
•2. Patients with a pacemaker or ICD
•3. Indication for ICD therapy according to the European Society of Cardiology (ESC) guidelines
•4. Life expectancy of less than one year
•5. Significant coronary artery disease or myocardial infarction < 3 months
•6. Complex congenital heart disease
•7. Pregnancy

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