NCT00968305已完成不适用
Cytokine Production in Children With Asthma.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- Interleukin-13 from phytohemagglutinin activated peripheral blood mononuclear cells
研究概览
简要总结
Asthma is a very common childhood chronic illness and is generally more severe in African Americans. The investigators attempted to determine whether a specific immune marker is associated with lung function and asthma severity.
详细描述
This study examined the relationship between Interleukin (IL)-13 from phytohemagglutinin-activated polymorphonuclear blood cells and asthma severity, lung function (measured as FEV1%), and total serum IgE levels in African American children with clinically diagnosed asthma
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 8 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •African-American race, born in the U.S.
- •Age 8-15 years
- •Clinical diagnosis of asthma
- •Subject is able to understand and follow verbal instructions in English
排除标准
- •Asthma exacerbation in the 4 weeks preceding the research visit
- •Oral/IV steroid use in the 4 weeks preceding the research visit
- •Upper or lower respiratory tract infection in the 4 weeks preceding the research visit
- •Antibiotic use in the 4 weeks preceding the research visit
- •Use of a short-acting bronchodilator during the 6 hours prior to spirometry (lung function testing)
- •Use of a long-acting bronchodilator during the 12 hours prior to spirometry (lung function testing)
结局指标
主要结局
Interleukin-13 from phytohemagglutinin activated peripheral blood mononuclear cells
时间窗: 7 months (from the start to completion of study. The blood was drawn at the one and only visit for each subject)
次要结局
- Lung function measured by percent predicted forced expiratory volume in the first second (FEV1%)(7 months (from the start to completion of study, but FEV1% was measured at the one and only visit for each subject))
研究者
研究点 (1)
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