Pilot study to identify potential saliva-based biomarkers for diagnosis of neonatal sepsis.

Spot Healthcare Solutions Pvt Ltd0 个研究点目标入组 100 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•The inclusion criteria will include all neonate who show clinical symptoms for sepsis (i.e any two of the following symptoms: respiratory distress, temperature fluctuation, diarrhea, reduced movements, reduced sucking, seizures, bradycardia, swollen belly area, heart rate >160). A hematological sepsis screen (as per section 8.4.2) and blood culture will be conducted.
•The obtained sample groups will be categorized in following sections
•1. Serum samples showing positive results for sepsis screen and positive results for blood culture
•2. Serum samples showing positive results for sepsis screen but negative results for blood culture
•Diagnosis of sepsis will be confirmed for neonates showing positive result for sepsis screen and a positive result for blood culture.
•CONTROL GROUP: 50 age and sex matched healthy neonates (showing no clinical symptom for sepsis) will be recruited as the control group for this study.

•Neonates who exhibit clinical symptoms for or have been identified with the following will be excluded from this study
•1. Congenital malformation
•2. Intraventricular bleed
•3. Chronic lung disease
•4. Perinatal asphyxia
•5. Meconium aspiration syndrome
•6. Chromosomal malformations

发起方

Spot Healthcare Solutions Pvt Ltd