NCT01152892Unknown不适用
Risk Stratification in End Stage Renal Disease (ISAR)
Technical University of Munich17 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2010年4月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 500
- 试验地点
- 17
- 主要终点
- Mortality of all causes
研究概览
简要总结
The purpose of this study is to evaluate the use of non-invasive markers of the autonomic function and micro- and macrocirculation to predict mortality and cardiovascular end points in end-stage renal disease patients. Furthermore we aim at getting new insight into the insufficiently understood pathophysiology leading to excessively high cardiovascular and non-cardiovascular mortality in dialysis patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 or older
- •End-stage renal disease (ESRD) and receiving maintenance hemodialysis
排除标准
- •Any clinically significant infection.
- •history of malignant disease with a prognostic life expectancy less than 24 months
- •missing of written and informed consent
结局指标
主要结局
Mortality of all causes
时间窗: 24 months
24 month follow up
次要结局
- Incidence of cardiovascular events(24 months)
- Blood pressure drops within a dialysis session(24 months)
- Incidence of infections requiring antibiotic treatment(24 months)
- Incidence of shunt thrombosis(24 months)
- incidence of death and hospitalization due to infection(24 months)
研究者
PD Dr. Christoph Schmaderer
PD Dr. med. Christoph Schmaderer
Technical University of Munich
研究点 (17)
Loading locations...
相似试验
已完成
不适用
Evaluation of Candidate Biomarkers to Predict Disease Severity and Acute Kidney Injury in Sepsis PatientsAcute Kidney InjurySeptic ShockSepsisNCT05310812Istanbul University140
已完成
不适用
Renal Cell Arrest and Damage Biomarkers in Progression and Outcome of Septic AKIAKI - Acute Kidney InjuryNCT06064487Alexandria University80
Enrolling By Invitation
不适用
Non-Invasive Bioelectronic AnalyticsAutonomic DysfunctionAutonomic ImbalanceAutonomic Nervous System DiseasesVagus Nerve Autonomic DisorderNCT04100486Northwell Health48
已完成
不适用
Cardiac Autonomic Function For Risk Stratification in the Emergency RoomAutonomic Nervous System ActivityNCT01486589Thebiosignals.com6,521
撤回
不适用
Autonomic and cardiac function in end stage renal disease patients: A pilot studyautonomic functionheart function100192801003843010003184NL-OMON37476Maxima Medisch Centrum20