Channel Detection to Predict Ventricular Arrhythmia in Patients With Non-ischemic Cardiomyopathy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 主要终点
- Detect pro arrhythmogenic scar characteristics
研究概览
简要总结
Sudden cardiac death (SCD) risk stratification is a challenge in non-ischemic cardiomyopathy (NICM). The underlying mechanism of monomorphic ventricular tachycardia (VT) is mostly scar related. While electrophysiological mechanisms underlying ventricular arrhythmia are well known, late gadolinium enhanced (LGE) cardiac MRI-3D reconstructions are now able to guide VT ablation procedures. Such exam may help in identifying specific properties of scar at risk of malignant arrhythmia.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult with NICM
- •Previous history of ventricular tachycardia (VT) and no previous history of VT
排除标准
- •Inherited cardiomyopathies
- •Previous history of myocarditis WITHOUT oedema/scar at the MRI
结局指标
主要结局
Detect pro arrhythmogenic scar characteristics
时间窗: baseline : collected at the time of the cardiac MRI
The outcomes will aim to provide scar characteristics from 3D cardiac MRI reconstructions to detect pro arrhythmic properties in NICM patients. Comparisons between NICM patients who experienced VT ablation and NICM patients without history of ventricular arrhythmia will be made. In both groups, Primary outcome will aim to measure the number of the conducting channels into scars (n).
次要结局
未报告次要终点