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临床试验/NCT03887364
NCT03887364已完成不适用

Effect of Ice and Airflow Stimulation Versus Controlled Breathing Exercises to Reduce Dyspnea in Patients With Obstructive Lung Disease

Riphah International University2 个研究点 分布在 1 个国家目标入组 126 人开始时间: 2018年2月2日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
126
试验地点
2
主要终点
Forced Expiratory Volume in 1 second (FEV1)

研究概览

简要总结

A randomized controlled trial in which icing and airflow stimulation for reduction of dyspnea in patients of obstructive lung disease was done which is characterized as condition of infection described by constant improvement of perpetual constraint of flow of air that is partially reversible and incorporates chronic bronchitis, emphysema and small airway diseases . The tools used were RR, Spirometry, Saturation, Borg Scale, MRC scale, shuttle walk test and St George's Respiratory Questionnaire (St.GRQ) score. Pulse oximeter measured the saturation levels and respiratory rates were alse observed. Borg scale measured rate of perceived exertion ranges from 6(easy physical activity) and 20(worst activity) and MRC measure dyspnea levels. In St.GRQ score between 1 to 8 is symptoms related and 9 to 17 was activity related.Literature review indicate that icing and airflow stimulation reduce dyspnea in patients of obstructive lung diseases.

详细描述

Constant obstructive Pulmonary disease (COPD) is an essential reason of mortality and bleakness everywhere throughout the world. In United States, COPD stands third in the causes of mortality with annual 100,000 deaths .An estimated 15 million people had COPD diagnosed with health care provider in 2010 and un-diagnosed cases are 12 million in number. In China ,COPD stands first among disability causes and becoming a reason of public health attention.According to an interpretation COPD overall rate of prevalence is 8.2% in China mortality rate of COPD is 1.6%.

In 12 countries/Cities of Asia-Pacific localies Model Projections of the commonness of Moderate-to-Severe instances of COPD in Those Persons > 30 years af age was total of 56,553,000 with total prevalance of 6.30%.Data are from the study held by the COPD regional working group.

Pakistan is a lower-middle-income country with a population of 182.1 million Pakistan, has a high load of chronic respiratory diseases a lower-middle-income country, with a population of 182.1 million. Age standardized death rate due to respiratory diseases is 138.2 per 100,000 in men and 41.3 per 100,000 in women in Pakistan.

"Effects of smoking mediation and the utilization of a breathed in anticholinergic bronchodilator on the rate of decrease of FEV1" presuming that This single intercession with the most extreme ability to impact the common history of COPD.in a lung wellbeing study assessment of the smoking suspension part demonstrates that if appropriate assets and time are given to end of smoking 25% quit rates can be picked up for long term.

an investigation in 2002 with the title of "Treating tobacco utilize and reliance" deriving that the act of conveying end of smoking help ought to take after "five A's" standards. The "five A's" of smoking discontinuance are Ask about utilization of tobacco, Advise to stop, Assess ability to influence an endeavor, To aid stop endeavor, Arrange development.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
30 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patient having mild to moderate stage of COPD

排除标准

  • Any facial injury and surgery.
  • Sinusitis.
  • Patient with respiratory failure.
  • Patient having dyspnea on cardiac origin
  • Patient having allergic rhinitis and Bronchitis.
  • Patients having cystic fibrosis

研究组 & 干预措施

Group A-Diaphragmatic breathing exercise

Active Comparator

Diaphragmatic breathing exercise

干预措施: Group A-Diaphragmatic breathing (Other)

Group B-Icing and Airflow Stimulation

Experimental

Icing and Airflow Stimulation

干预措施: Group B-Icing and Airflow Stimulation (Other)

结局指标

主要结局

Forced Expiratory Volume in 1 second (FEV1)

时间窗: 4 weeks

Changes from the Baseline, the digital spirometer is used in clinical setting to analyze Forced Expiratory Volume in 1 second FEV1 in Liters

Peak Expiratory Flow (PEF)

时间窗: 4 weeks

Changes from the Baseline, the digital spirometer is used in clinical setting to analyze peak expiratory flow PEF in Liter/second.

Forced vital Capacity (FVC)

时间窗: 4 weeks

Changes from the Baseline, the digital spirometer is used in clinical setting to analyze Forced vital Capacity in Liters

次要结局

  • Oxygen Saturation (SpO2)(4 weeks)
  • Medical Research Council (MRC) Breathlessness scale(4 weeks)
  • ST. GEORGE RESPIRATORY QUESTIONAIRE(4 weeks)
  • Respiratory Rate(4 week)
  • BORG SCALE(4 weeks)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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