Albumin in acute-on-chronic liver failure: More than just volume?A randomized, controlled study - Albumin in ACLF

Medical University Graz0 个研究点开始时间: 2007年8月17日最近更新: 2015年7月10日

适应症

试验速览

暂无简介。

•Patients with a clinical, radiological and/or histological evidence of cirrhosis and a polymorphonuclear-cell count in the ascitic fluid of more than 250 per cubic millimeter (spontaneous bacterial peritonitis, SBP)
•Age above 18
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years)
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years)
•F.1.3.1 Number of subjects for this age range

•findings suggestive of secondary peritonitis
•antibiotic treatment within one week before the diagnosis of spontaneous bacterial peritonitis (except for prophylactic treatment with norfloxacin/levofloxacin)
•presence of infections other than spontaneous bacterial peritonitis
•gastrointestinal bleeding within last 14 days
•shock, cardiac failure (inotrope requirement)
•hepatic encephalopathy grade >2
•findings suggestive of organic nephropathy or a serum creatinine level of no more than 150 µmol per liter
•human immunodeficiency virus infection
•any disease (e.g., advanced neoplasia) that could affect the short-term prognosis
•potential causes of dehydration (such as diarrhea or an intense response to diuretic treatment) within one week before the diagnosis of peritonitis.

发起方

Medical University Graz