Comparison Efficacy in Patients With Asthma Using Foster MDI and Relvar Medications
试验速览
- 阶段
- 4 期
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Lung function improvement
研究概览
简要总结
This is a randomized study to compare asthma patients using Foster or Relvar.
详细描述
The Global Asthma Association (GAA) and the World Allergy Organization (WAO) recently issued statements stating that the small airway is caused by asthma and chronic obstructive pulmonary disease (COPD). Both pathogenesis and treatment play an important role. The small airway is an airway with diameter less than 2 mm and is one of the main sites where airflow obstruction occurs. Small particles (<2 μm) and large particles are more likely to deposit in the distal airways, and have shown to have better effects on asthma and pulmonary obstruction. At the same time, real-life research has also shown that extra-fine particles provide better asthma control than large particles, and can better improve quality of life.The aim of the study is to compare the efficacy of asthma inhalers between extra-fine particles and non-extra-fine particles.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients diagnosis with asthma with treatment naive
- •asthma patients with poor controlled status
排除标准
- •smoking history
- •pregnancy
- •cardiaovascular disease
- •patients with acute respiratory infection
研究组 & 干预措施
Foster
uncontrolled asthma patients were randomized into Foster treatment group
干预措施: Foster (Drug)
Relvar
uncontrolled asthma patients were randomized into Relvar treatment group
干预措施: Foster (Drug)
结局指标
主要结局
Lung function improvement
时间窗: one year
FEV1
次要结局
未报告次要终点
研究者
Shih-Lung Cheng
MD. PhD
Far Eastern Memorial Hospital