Diagnostic CT Palliative Radiotherapy: Feasibility Study of Treating Bone Metastases
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 10
- 主要终点
- dosimetric accuracy of palliative radiotherapy designed on a dCT compared to a CT simulation
研究概览
简要总结
The purpose of this non-randomized, prospective study is to assess the feasibility of planning and delivering conventional palliative radiotherapy to bone metastases on previously available diagnostic CT scans (dCT).
Objectives:1) dosimetric accuracy of palliative radiotherapy designed on a dCT compared to a CT simulation 2) assess suitability of patient set up using surface landmarks and kilo voltage (kV) imaging 3) determine the proportion of patients who can receive radiotherapy designed on a dCT 4) confirm eligibility criteria for appropriate patients in clinical practice
All enrolled patients will undergo a CT simulation with tattoos as per current standard of care.The radiation oncologist will place fields on the dCT and CT simulation. Radiotherapy will be planned on both CT scans and reviewed for quality by both the radiation oncologist and medical physicist.
详细描述
Purpose:
This prospective study aims to demonstrate the feasibility of delivering palliative radiotherapy designed on a diagnostic CT scan (dCT) for patients with bone metastases in the spine and bony pelvis.
Hypothesis:
At least eighty percent of patients will successfully receive radiotherapy as designed on the dCT.
Justification:
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients >18 years of age
- •Able to provide informed consent
- •Patient able to lie supine comfortably
- •Patient is receiving conventional palliative radiotherapy (Parallel Opposed Pair or single field over 8/1 or 20/5) for the treatment of bone metastases in the following locations: T5-lumbosacral spine, Bony pelvis
- •Patient has a diagnostic CT scan which includes the anatomic location to be treated that is within 28 days of enrollment
- •Quality of dCT scan is deemed sufficient for RT planning as determined by medical physicist and RT
排除标准
- •Patient unwilling, unable to consent to treatment/study
- •Any contraindications to receiving radiotherapy including pregnancy
- •Oncologic emergencies, on call treatments, or any indications for urgent radiotherapy
- •Inability to comfortably maintain and immobilized position due to uncontrolled pain or co-morbidities
- •Cases requiring VMAT planning or complex planning to account for prior courses of radiotherapy
- •Cases using non-conventional palliative radiotherapy fractionations
- •Anatomic sites outside of the pre-defined criteria above
结局指标
主要结局
dosimetric accuracy of palliative radiotherapy designed on a dCT compared to a CT simulation
时间窗: 1 Year
assess suitability of patient set up using surface landmarks and kilo voltage (kV) imaging
时间窗: 1 Year
determine the proportion of patients who can receive radiotherapy designed on a dCT
时间窗: 1 Year
confirm eligibility criteria for appropriate patients in clinical practice
时间窗: 1 Year
次要结局
- patient satisfaction with treatment process(1 Year)
- evaluate carbon footprint savings of dCT-RT workflow(1 Year)