PACTR201611001859416已完成未知
A randomised controlled trial to investigate the efficacy, safety and tolerability of adding a single low primaquine dose to artemether-lumefantrine for the treatment of symptomatic uncomplicated Plasmodium falciparum malaria
niversity of Cape Town0 个研究点目标入组 140 人开始时间: 2016年11月11日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 140
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 2 Year(s) 至 100 Year(s)（—）
- 性别
- All
入选标准
- •Plasmodium falciparum positive by RDT
- •Age > 2 years
- •Weight over 10 kg
- •Prescribed artemether-lumefantrine according to standard practice
- •Informed consent (by legally acceptable representative if under 18 years of age)
- •Assent in children aged 7 and above
- •Intention to remain in the study area for the duration of the follow-up period
排除标准
- •Evidence of severe illness/ danger signs
- •Known allergy to study medications
- •Medical history of haemolysis, rheumatoid arthritis, lupus erythematosus or cardiac disease
- •In patients receiving concurrently other drugs that are cause hemolysis, bone marrow suppression or QTc interval prolongation
- •Hb < 7 g/dL
- •A decrease in Hb of > 2 g/dL between day 0 and day 3 prior to primaquine dose
- •Currently menstruating
- •Pregnant or breastfeeding
- •History of any antimalarials (including primaquine) taken within the last 4 weeks
- •Blood transfusion within the last 90 days
研究者
相似试验
招募中
不适用
Reducing disability in older Australians through secondary stroke prevention.ACTRN12611000264987ational Ageing Research Institute (NARI) of Melbourne.300
已完成
不适用
A study to investigate the effect of an ergonomic seat on blood flow in the lower legs.Deep vein thrombosisOther - Research that is not of generic health relevance and not applicable to specific health categories listed aboveACTRN12607000621415ErgoCentric Seating Systems12
已完成
不适用
The effect of a year 9 and 10 high school program, Headstrong, on adolescent depression and mental health literacy.Depression literacyHelp seekingStigmaPsychological distressResilienceMental Health - DepressionSuicidal ideationACTRN12613000823774Professor Helen Christensen1,500
已完成
不适用
The effects of lipid-based multiple micronutrients on the health of children in the developing worldISRCTN73571031Medical Research Council (MRC) (UK)2,250
已完成
不适用
A randomised controlled trial to investigate the effect of regular moderate intensity exercise on plasma fibrinogen in people with type two diabetes: a pilot studyType two diabetesNutritional, Metabolic, EndocrineNon-insulin-dependent diabetes mellitusISRCTN98564438Department of Health80