跳至主要内容
临床试验/NCT02695914
NCT02695914Unknown不适用

Inflammatory Markers in Patient of FUO With Excess-heat Syndrome and the Influence of Compound Qingre Granule on the Inflammatory Markers

Beijing Friendship Hospital0 个研究点目标入组 80 人开始时间: 2016年1月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
入组人数
80
主要终点
Inflammatory marker (TREM-1) in patient of FUO

研究概览

简要总结

The purpose of this study is to observe inflammatory markers like TNF (tumor necrosis factor), IL-1 (interleukin-1), IL-6 (interleukin-6),TREM-1 (triggering receptor expressed on myeloid cells-1), etc, in patient of FUO with excess-heat syndrome and the influence of Compound Qingre Granule on the inflammatory markers.

详细描述

All the cases will be provided by the Infectious Diseases Department of Beijing Friendship Hospital.Each patient should sign informed consent. Assessing the accuracy, completeness, or representativeness of registry data by comparing the data to medical records. After collecting, sorting and entering the data, reducing the missing value, and then checking into the database.

The stochastic indicator method will be used to simple random sampling, to ensure the probabilities of each individuals be given Chinese medicine intervention are equal.Operations must be standard to reduce errors.

Quality assurance plan: Patient of fever within two weeks, or whose temperature is below 38.5 degree centigrade will be excluded. The registration form includes the following parts: Name, sex, age, address, phone number, admission time, primary diagnoses and levels of Inflammatory markers.

Data will be analyzed using the SPSS17.0 (Statistical Product and Service Solutions 17.0) statistical software. Difference of measurement data will be compared with analysis of variance,and difference of enumeration data will be compared with rank-sum test.P<0.05 has statistical significance.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Patient of fever of unknown origin (FUO).

排除标准

  • Patient of fever within two weeks, or whose temperature is below 38.5 degree centigrade.

研究组 & 干预措施

Experiment group

On the base of control group, Compound Qingre Granule will be added to in experiment group.

干预措施: Compound Qingre Granule (Drug)

结局指标

主要结局

Inflammatory marker (TREM-1) in patient of FUO

时间窗: 7th day

次要结局

  • Inflammatory marker (TNF) in patient of FUO(7th day)
  • Inflammatory marker (IL-1) in patient of FUO(7th day)
  • Inflammatory marker (IL-6) in patient of FUO(7th day)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Miao Shi

postgraduate

Beijing Friendship Hospital

相似试验