Development and Evaluation of Smartphone App for Initiation of Protective Ventilation. Clinical Impact of Instrumental Dead Space Reduction on Physiologic Parameter Based on the Smartphone App
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- PaCO2 Variation
研究概览
简要总结
Clinical evaluation of a new educative tools (Smartphone application) based on impact of instrumental dead space reduction after initiation of protective ventilation during mechanical ventilation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years old
- •Mechanical ventilation (control,assist control or SIMV mode)
- •haemodynamic stability (vasopressor < 0.2 ug/kg/min)
- •no prone position schedule in the next 2 hours following procedure inclusion
- •presence of an Arterial catheter
排除标准
- •ECMO or anticipate ECMO
- •body temperature < 36.0 for post operative patient (cardiac surgery)
研究组 & 干预措施
Protective ventilation with HME
Protective ventilation + HME
干预措施: Protective ventilation with HME (Procedure)
Protective ventilation with Heated humidifier
Protective ventilation + HH
干预措施: Protective ventilation with Heated humidifier (Procedure)
Implementation of protective ventilation
Protective ventilation implementation
干预措施: Protective ventilation implementation (Procedure)
Tidal Volume reduction
Tidal volume reduction
干预措施: Tidal Volume reduction (Procedure)
结局指标
主要结局
PaCO2 Variation
时间窗: 120 minutes post intervention
The primary outcome is to evaluate the PaCO2 variation at the end of condition 2 (after 30 minutes with protective ventilation+ HME) and condition 4 (30 minutes after Tidal volume reduction + Heater humidifier). Variation \<= 10% of PaCO2
PaCO2 Variation
时间窗: 60 minutes post intervention
The primary outcome is to evaluate the PaCO2 variation at the end of condition 2 (after 30 minutes with protective ventilation+ HME) and condition 4 (30 minutes after Tidal volume reduction + Heater humidifier). Variation \<= 10% of PaCO2
次要结局
- Hemodynamic impact vs pH(Baseline, 30, 60, 90 and 120 minutes post intervention)
- Correlation between PCO2 variation and alveolar ventilation variation(60 and 90 minutes post intervention)