NCT06592196招募中不适用
A Retrospective Study on the Hepatic Safety of Statin Use in Neurology Inpatients
Shanghai Yueyang Integrated Medicine Hospital1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2024年8月10日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- Aspartate aminotransferase(AST)
研究概览
简要总结
This research employs a cross-sectional study and a retrospective cohort study to analyze the liver safety of statin use among inpatients in the neurology department in China from different perspectives. The aim is to supplement evidence-based medicine and provide guidance for the clinical use of statins.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients hospitalized in the Department of Neurology of Yueyang Hospital from June 2020 to February
- •Age ≥18 and ≤85 years old, both sexes.
- •Meet the diagnostic criteria of cerebrovascular disease (L1-8B0), headache disease (L1-8A8) and dizziness and vertigo (MB48) in ICD-11.
排除标准
- •Incomplete medical history.
- •1 days ≤ patients with < 7 days of prior statin use.
- •Patients with malignant tumors (ICD-11 code L1-2A0, L1-2A2, L1-2B5, L1-2E6 diseases) and hematological diseases (ICD-11 code L1-3A0, L1-3B1, L1-3B8 diseases).
结局指标
主要结局
Aspartate aminotransferase(AST)
时间窗: 4weeks after admission.
The specific value of AST, whether the AST was more than 1 times the upper limit of normal (\>1×ULN), and whether it was more than 3×ULN.
Alanine aminotransferase(ALT)
时间窗: 4 weeks taken after admission.
The specific value of ALT, whether the ALT was more than 1 times the upper limit of normal (\>1×ULN), and whether it was more than 3×ULN.
次要结局
未报告次要终点
研究者
研究点 (1)
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