Liver Transplantation in Haemophilia Patients in Spain
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 11
- 主要终点
- Number of Participants Requiring Immunosuppressive Therapy After Liver Transplantation
研究概览
简要总结
This study will analyze survival and outcome of patients with severe haemophilia who undergo liver transplantation in Spain
详细描述
Probability Sample
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with haemophilia who underwent liver transplantation and who have been followed-up at any site in Spain.
排除标准
- •Patients without informed consent form.
结局指标
主要结局
Number of Participants Requiring Immunosuppressive Therapy After Liver Transplantation
时间窗: Post liver transplantation up to Month 3
Cyclosporine, corticosteroids, tacrolimus, mycophenolate mofetil, everolimus were considered as immunosuppressive therapy after liver transplantation.
Number of Participants With Acute Rejection of Liver Transplant
时间窗: Post liver transplantation up to Month 3
Any acute rejection of the liver transplant was clinically suspected and biopsy proven by central pathologist.
Number of Participants With Hepatitis C Viral Infection Recurrence After Liver Transplantation
时间窗: Post liver transplantation up to Month 3
Number of participants who had liver transplantation after cirrhosis due to hepatitis C virus (HCV) infection and experienced recurrence of HCV infection post liver transplantation.
Number of Participants Who Survived After Liver Transplantation
时间窗: Post liver transplantation up to Month 3
Number of participants who survived after liver transplantation was reported. The death reported was a result of acute-related transplantation complications and end-stage liver disease.
次要结局
- Number of Participants Requiring Exogenous Clotting Factor Infusion During Liver Transplantation(Up to Day 5 post liver transplantation)
- Dose of Exogenous Clotting Factors Used During Liver Transplantation(Up to Day 5 post liver transplantation)
- Number of Participants With and Without Hemophilia Requiring Immunosuppressive Therapy, Had Acute Rejection, Hepatitis C Viral Infection Recurrence and Who Survived After Liver Transplantation(Post liver transplantation up to Month 3)