Assessment of the predictive value of BNP/ NT-proBNP Thresholds vs NT-proBNP with and without Acute Heart Failure Cases.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- A predictive biomarker that is simple to use to detect acute Heart Failure.
研究概览
简要总结
**Background:**Diagnosis and treatment of acute heartfailure (AHF) is an important task for cardiologists. Diagnostic tests includebiomarkers such as N-terminal B-type natriuretic peptide (NT-proBNP) and brainnatriuretic peptide (BNP). Comparison of BNP/NT-proBNP thresholds in AHF andnon-AHF patients may aid in diagnosis.
**Objective:**We sought to evaluate the predictiveutility of NT-proBNP and BNP/NT-proBNP thresholds in patients with and without HF.This study evaluated and compared the predictive ability of serial NT-proBNPmeasurements and BNP/NT-proBNP threshold in patients with and without heartfailure.
**Methods:**A cross-sectional study will include 50patients hospitalized at Acharya Vinoba Bhave Rural Hospital and JawaharlalNehru Medical College and 50 controls. These will include patients with andwithout severe HF. Data on BNP and NT-proBNP levels and clinical outcomes willbe collected.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 30.00 Year(s) 至 85.00 Year(s)（—）
- 性别
- All
入选标准
- •The Age criteria of patients is above 30 years.
- •Indian citizen.
- •Acute heart failure cases, according to Framingham Diagnostic Criteria, one major and two minor criteria symptoms are found in patients within six weeks, with physical examination and echocardiography.
- •The Ability for the patients to provide a written consent form.
排除标准
- •Pregnant patients will be excluded
- •Chronic Kidney disease
- •Chronic Alcoholics
- •Liver disease
- •Cancer patients
- •Malignancy
- •Patients who are not willing to give informed consent.
结局指标
主要结局
A predictive biomarker that is simple to use to detect acute Heart Failure.
时间窗: Assessment will be done at the time of admission after 24 hrs. overall study assessment will be done within 6 months
次要结局
未报告次要终点