CTRI/2022/10/046482招募中不适用
Correlation of delta rectus femoris thickness with weaning failure in critically ill mechanically ventilated patients
Bharati Hospital and Research center1 个研究点 分布在 1 个国家目标入组 136 人开始时间: 2022年10月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 136
- 试验地点
- 1
- 主要终点
- Weaning Failure after first spontaneous breathing trial
研究概览
简要总结
There are small studies suggesting a correlation between difference in skeletal muscle thickness (rectus femoris + vastus intermedius), diaphragmatic thickness and excursion with weaning failure. As measurement of diaphragmatic thickness and excursion is difficult we have planned to determine correlation between USG guided delta rectus femoris muscle thickness and weaning failure in critically ill mechanically ventilated patients.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •i.Age above 18 years.
- •ii.Patients requiring more than 24 hours of mechanical ventilation on admission or within 24 hours of admission.
排除标准
- •i.Patients with trauma to bilateral thighs for eg- degloving injuries, burns, fractures etc.
- •ii.Patients with known neuromuscular disorders, stroke, previously diagnosed critical illness neuropathy, unilateral or bilateral swelling in the legs.
- •iii.Patients with history of chronic organ failures, malignancy and pregnancy.
结局指标
主要结局
Weaning Failure after first spontaneous breathing trial
时间窗: At baseline, within 24 hours of first spontaneous breathing trial
次要结局
- •To measure length of ICU stay, ventilator free days and 28-day mortality in all patients.(2 years)
研究者
研究点 (1)
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