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临床试验/NCT05574231
NCT05574231尚未招募不适用

A Danish Nationwide Longitudinal Registered Based Study on Prevalence, Treatment Patterns and Disease Trajectories of Periodontitis and Co-morbidities 'PlanPerioMed'

University of Copenhagen0 个研究点目标入组 4,000,000 人开始时间: 2022年11月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
4,000,000
主要终点
Effect on medical diseases

研究概览

简要总结

The project (PlanPerioMed) is a register-based study evaluating the associations and patterns of health care delivery between periodontitis and medical diseases using data from the Danish dental record system Dentalsuite (Plandent A/S) and national Danish health care registries with three overall hypotheses/ aims:

  • Determine the extent to which periodontitis in registry data is associated with more odontological treatment services and treatment frequency.
  • Determine if patients with systemic diseases attend dentists more frequently and receive more treatment services per patient than the population without these diseases.
  • Determine to which extent periodontitis and received periodontal treatment affects the risk of medical diseases.

The study will focus on association and trajectories of periodontitis and its treatment with three medical diseases, namely, Type 2 Diabetes Mellitus (Type 2 DM), Cardiovascular Diseases (CVD) and Rheumatoid Arthritis (RA). The dataset consists of approximately 4,000,000 people aged between 18 and 99 years attending private practice in Denmark. The results from PlanPerioMed study are likely to have ramifications for treatment guidelines for other periodontitis comorbidities, e.g. CVD and DM, and will thereby improve the quality of life for a wide range of patients and reduce long-term societal health care expenses related to periodontitis and its comorbidities.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

年龄范围
18 Years 至 99 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Subjects with clinical registrations of DMFT, periodontal status and corresponding treatment codes
  • Self-reported systemic diseases including Diabetes Mellitus Type 2, Cardiovascular Diseases and Rheumatoid Arthritis
  • Subjects with Clinical Attachment Loss>=3mm, Probing Depth >= 3mm and bleeding on probing (as defined by World Workshop 2017- criteria for periodontitis) in clinical examination will be included in the study population.

排除标准

  • Subjects with more than 32 teeth
  • Subjects with no clinical registrations

结局指标

主要结局

Effect on medical diseases

时间窗: 25 years

Risk of medical diseases based on periodontal disease extent and received periodontal treatment

Treatment frequency and type of treatment services

时间窗: 25 years

Number of treatment and odontological treatment services due to periodontitis

Treatment frequency and type of treatment services among patients with medical diseases

时间窗: 25 years

Number of treatment and odontological treatment services among patients with medical diseases due to periodontitis

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Christian Damgaard

Associate professor, Head of Section

University of Copenhagen

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