Menopausal Treatment Using Relaxation Exercises (MaTURE)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 123
- 试验地点
- 2
- 主要终点
- Change in average daily frequency of hot flashes.
研究概览
简要总结
Hot flashes occur in as many as two thirds of U.S. women during menopause and are severe enough to require treatment in 20%. Although postmenopausal hormone therapy is effective in suppressing hot flashes, it is associated with increased risk for a variety of serious adverse effects. There is an urgent need for alternative treatments that are effective, safe, and easy to use. In this study, the investigators will compare two different types of behavioral relaxation therapies, paced respiration and music therapy, for treatment of menopausal hot flashes. Effects on frequency of hot flashes, other symptom and quality-of-life outcomes associated with hot flashes, and physiologic measures of sympathetic/parasympathetic activity will be examined.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 59 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Change in average daily frequency of hot flashes.
时间窗: 4-Weeks and 12-Weeks
次要结局
- Change in subjective severity of hot flashes.(4-weeks and 12-weeks)
- Change in sympathetic and parasympathetic autonomic nervous system tone.(12 weeks)
- Change in quality-of-of life measures associated with hot flashes.(Weeks 4 and Weeks 12)
研究者
Deborah Grady
Professor of Medicine
University of California, San Francisco
