Pennington Generation Cohort
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 3,000
- 试验地点
- 2
- 主要终点
- Obesity
研究概览
简要总结
The Pennington Generation Cohort is an observational study comprised of Louisiana families. Families will be assessed at baseline for a variety of traits and behaviors, and then followed up over time to try to understand the role of lifestyle and the environment on the risk of developing obesity and other health outcomes.
详细描述
Pennington Biomedical's Greaux Healthy initiative partners with communities to grow healthier generations by expanding the access and reach of Pennington Biomedical's evidence-based practices for the prevention and treatment of childhood obesity. As part of Greaux Healthy, the Pennington Generation Cohort will help evaluate the impact of the program. A sample of up to 1,500 children and adolescents and their families will be recruited from throughout Louisiana. An initial physical exam will establish a baseline for each family with respect to lifestyle behaviors, genetics, and body size/composition. This longitudinal cohort will also assess the association between participation in several childhood obesity prevention and treatment programs and subsequent obesity and related health outcomes. Members of the longitudinal cohort will be followed in the future through clinical visits, questionnaires, and through optional linkages to electronic medical records and administrative databases such as the National Death Index, Social Security Death Master File, and health registry data.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children, adolescents, and young adults (birth through age 24 years) and their nuclear family members* and adults age 25+ who are expectant parents or are trying to conceive
- •Self-reported resident of Louisiana
- •Ability to understand instructions and complete all study procedures
- •Able to provide informed consent (adults aged over 18 years)
- •Able to provide assent (children 9 to 17 years)
- •Able to communicate (oral and written) in English
排除标准
- •Discretion of the Medical Monitor or Principal Investigator
结局指标
主要结局
Obesity
时间窗: From enrollment up to 20 years of follow-up.
The development of obesity, defined using BMI z-scores during childhood, and BMI during adulthood.
次要结局
- Weight change(From enrollment up to 20 years of follow-up.)
- Mortality(From enrollment up to 20 years of follow-up..)
- Cancer incidence(From enrollment up to 20 years of follow-up..)
研究者
Peter T. Katzmarzyk
Professor
Pennington Biomedical Research Center