Retrospective Analysis of Causes, Clinical Presentation and Treatment in Patients With Hypercalcaemia in the Emergency Department of a Tertiary German Hospital
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Development of total calcium values
研究概览
简要总结
Patients with hypercalcemia were identified in the patient population of a German emergency department during a 11 year time period and studied regarding reproducibility of elevated calcium values, causes of hypercalcemia, symptoms. acute renal injury, mortality and treatment response.
详细描述
Patients, who presented to the emergency department of a tertiary German hospital with a total calcium of ≥2.65 mmol/l between January 2010 and March 2021, was retrospectively studied. From the electronic patient records we analyzed if the elevated calcium values were reproducible in follow-up measurements, identified the cause of hypercalcemia, listed the symptoms, investigated a correlation between calcium and creatinine values to study acute renal injury directly due to hypercalcemia, calculated the mortality rate stratified by the calcium value on presentation and studied the treatment response regarding lowering calcium values by different treatments.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Total calcium ≥ 2.65 mmol/l
- •Female and male
排除标准
- •Age < 18 years
- •Total calcium < 2.65 mmol/
结局指标
主要结局
Development of total calcium values
时间窗: 5 days after enrollment
Overview of total calcium values within 5 days
次要结局
- Reproducibility of elevated calcium values(5 days after enrollment)
- Correlation creatinine calcium(5 days after enrollment)
- Mortality(5 days after enrollment)
研究者
Volker Burst
Prof. Dr. med.
University of Cologne