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临床试验/CTRI/2026/04/107716
CTRI/2026/04/107716尚未招募不适用

Study of effect of etonogestrel subdermal implant vs depot medroxyprogesterone acetate injection on menstrual bleeding patterns and uterine artery doppler changes

Dr Baba Saheb Ambedkar medical college Hospital Rohini Sector New Delhi1 个研究点 分布在 1 个国家目标入组 152 人开始时间: 2026年4月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
152
试验地点
1

研究概览

简要总结

This prospective randomized controlled study aims to compare the effects of the etonogestrel subdermal implant and depot medroxyprogesterone acetate injection on menstrual bleeding patterns and uterine artery Doppler indices among women seeking interval contraception. A total of 152 eligible women aged 20 to 40 years attending the Family Planning OPD of Dr Baba Saheb Ambedkar Hospital New Delhi will be enrolled and randomized in a one to one ratio to receive either the etonogestrel implant or depot medroxyprogesterone acetate injection. Participants will be followed for six months. Menstrual bleeding patterns will be recorded and uterine artery Doppler indices including pulsatility index resistance index and endometrial thickness will be measured at baseline three months and six months. The study aims to evaluate differences in bleeding patterns and Doppler changes between the two contraceptive methods and to assess side effects acceptability and reasons for discontinuation.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 45.00 Year(s)(—)
性别
Female

入选标准

  • Young women aged 20-40 years old who desired interval Contraception and having no contraindication for ENG implant or DMPA
  • No hormonal treatment for at least three months before insertion.
  • Patients who do not want to conceive for at least 1 year.

排除标准

  • Pregnancy
  • Past or current history of Breast cancer 3., Liver disease
  • Any Contraindication to progestin administration
  • Nulliparity 6.Pts with AUB ( Structural causes: PALM- Polyp, Adenomyosis, Leiomyoma (fibroid), Malignancy and hyperplasia and Nonstructural causes : COEIN :Coagulopathy, Ovulatory dysfunction, Endometrial, Iatrogenic, Not yet classified (or not otherwise classified)
  • Nulliparity.

研究者

发起方
Dr Baba Saheb Ambedkar medical college Hospital Rohini Sector New Delhi
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

DR ISHIKA CHITKARA

Dr Baba Saheb Ambedkar Medical college & Hospital, Rohini sector 6,, DELHI

研究点 (1)

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