NCT00754117已完成不适用
Early Response Assessment in Patients With Diffuse Large B-cell Lymphoma Using 18-fluoro-2-deoxyglycose Positron Emission Tomography (FDG-PET)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- evaluating the predictive value of a positive PET scan early in the course of standard chemotherapy
研究概览
简要总结
Newly diagnosed DLCL patients will have baselne FDG-PET as part of initial staging (PET-1). Patients will then undergo 2 cycles of chemotherapy with R/CHOP. 14 to 21 days following cycle 2 of R/CHOP, patients will undergo repeat FDG-PET scan (PET-2). They will then complete therapy as planned. Following completion of therapy, standard response assessment will be performed, including CT scans of the chest, abdomen and pelvis and FDG-PET scan (PET-3).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients must have histologically or cytologically confirmed diagnosis of CD20+ diffuse large B cell lymphoma (LBCL) of any stage, including subtypes mediastinal large B cell, centroblastic, immunoblastic, T cell rich B cell and anaplastic B cell lymphoma
- •Patients must have received no prior anti-lymphoma therapy.
- •Age >18 years.
- •Patients must have a treatment plan to include R/CHOP or R/CHOP followed by radiotherapy.
- •Ability to understand and the willingness to sign a written informed consent document.
排除标准
- •Patients who have known HIV infection.
- •Patients who are, in the opinion of their treating oncologist, unable to undergo R/CHOP chemotherapy.
结局指标
主要结局
evaluating the predictive value of a positive PET scan early in the course of standard chemotherapy
时间窗: after 2 cycles of chemotherapy
次要结局
未报告次要终点
研究者
研究点 (1)
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