Effect of Retrograde Autologous Blood Priming of Cardiopulmonary Bypass on Hemodynamic Parameters and Pulmonary Mechanics in Pediatric Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 124
- 主要终点
- Comparison of postoperative peak air way pressure between the studied groups
研究概览
简要总结
The present study hypothesized that beyond its hemodynamic affects,retrograde autologus blood priming of cardiopulmonary bypass (RAP) has a positive impact on hemodynamics and pulmonary mechanics subjected to cardiac surgery.
详细描述
This prospective randomized study analyzed the clinical records of 124 children subjected to cardiac surgery for congenital heart diseases with left to right shunt. They comprised 64 patients with RAP and 60 patients conventional cardiopulmonary bypass priming. The preoperative, intraoperative and postoperative data of the studied patients were reported.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
盲法说明
double-blind masking
入排标准
- 年龄范围
- 12 Months 至 5 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •children complained of congenital heart disease with left to right shunt pressure or volume load
排除标准
- •cyanotic heart disease
结局指标
主要结局
Comparison of postoperative peak air way pressure between the studied groups
时间窗: 1 hour after surgery
peak air way pressure (Paw) in cmH2O
Comparison of postoperative air way resistance between the studied groups
时间窗: 1 hour after surgery
air way resistance (Raw) in cmH2O/L/sec.
Comparison of postoperative Plateau pressure between the studied groups
时间窗: 1 hour after surgery
Plateau pressure in cm H2O
Comparison of postoperative Lung compliance between the studied groups
时间窗: 1 hour after surgery
Lung compliance in L/cm H2O
Comparison of postoperative Tidal volume between the studied groups
时间窗: 1 hour after surgery
Tidal volume in ml
次要结局
未报告次要终点
研究者
Dr. Hamdy Singab
Professor
Ain Shams University