Comparison the effectiveness of hydroxyethyl starch (voluven) solution versus normal saline in hemorrhagic shock treatment in trauma

Vice Chancellor for Research and Technology Development-Ahwaz Jondishapur University of Medical Sci0 个研究点目标入组 100 人开始时间: 待定最近更新: 2018年2月22日

适应症

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•The study included all patients with traumatic hemorrhagic shock who were referred to the Imam Khomeini hospital in Ahvaz, Iran. Exclusion criteria: Heart failure (reduced heart function with clinical symptoms: orthopnea, exertional dyspnea, MET <4 and EF <50%); Patient who received Blood before the study completed; Patient died before completing the study; Sensitivity to serum; Transfer to the operating room before the study completed; Hepatic insufficiency (decreased liver function with decreased albumin, increased PT, clinical and liver enzymes could be increased more than 5 times); Respiratory failure (lung function decline with increasing Pco2> 50 or drop in Po2 <60 or observed clinical signs of respiratory distress); Renal impairment: decreased renal function (GFR <60 mL/min/1.73 m2 for at least three months, or significant proteinuria); Sepsis: The presence of SIRS (Systemic Inflammatory Response Syndrome) with prove microbial etiology; Severe anemia (Hb <10); Patients who are considered for the diagnosis of non hemorrhagic shock; Patients with a history of sensitivity to the Solutions used in this study.

发起方

Vice Chancellor for Research and Technology Development-Ahwaz Jondishapur University of Medical Sci