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临床试验/NCT04172415
NCT04172415Unknown不适用

Current Procedural Sedation Practices for Adults and Children in a Canadian Community Emergency Department

Amber Graystone1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2019年11月30日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
300
试验地点
1
主要终点
Procedural Sedation

研究概览

简要总结

To review current Emergency Department procedural sedation practices in the community hospital setting and the associated drugs used (class of anesthetic and mode of administration). The ultimate goal of this investigation is to determine the need for a new analgesic/anesthesia drug and to compare the outcomes of a new drug within the same community Emergency Department setting. In particular, this may present a future opportunity to evaluate Penthrox (methoxyflurane) as a viable alternative for procedural sedation and analgesia in Canadian Emergency Departments.

详细描述

Procedural sedation is a common practice in the Emergency Department setting. The purpose of procedural sedation is to provide adequate pain relief to patients undergoing an emergent procedure. As a result, the time to the patient's symptom relief, the degree of side effects and the duration of action of the medication are all critical to selecting an appropriate sedative and/or analgesic.

The community hospital setting may present unique challenges to successfully administering procedural sedation techniques. Funding and resource allocation can limit patient access to timely sedation/analgesia. This can be compounded by prolonged stays in the Emergency Department for recovery and/or complications.

The current recommendations for 'Procedural Sedation and Analgesia in the Emergency Department' outlines recommended medications and policies for adults and children undergoing procedural sedation1,2. While a number of cohort and retrospective analyses have been done in a variety of research settings, the role for oral or intranasal anesthesia has not been adequately explored in ED settings. The initial phase of this research proposal will identify current local practices through chart review analysis collected over the last year. Subsequent research questions might include a comparative analysis of the current procedural sedation techniques compared to medications administered orally or by inhalation. This may have considerable future benefit to patient satisfaction and clinical outcomes, as well as resource and operational outcomes in the Emergency Department.

Hypothesis

To identify interventions requiring procedural sedation and the medication commonly used in a Canadian community emergency department (ED). Using standardized medical record review methods, primary clinical patient indicators, safety outcomes and secondary ED operational outcomes will be reviewed.3

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • patients who have registered in the Welland County General Hospital Emergency Department (WHS) from the dates of January 2017-December
  • Patients who require procedural sedation in the Emergency Department

排除标准

  • 未提供

结局指标

主要结局

Procedural Sedation

时间窗: 2 years

Total number of patients requiring conscious sedation

Medication Use

时间窗: 2 years

The number and type of medications used during procedure

Pre Procedural Assessment Findings

时间窗: 2 years

ASA score, 3-3-2 Abnormality, Pre-procedure Fast, Mallampatie Class, Neck Obesity, Facial Hair

Sedation Failures and Use of Rescue Medications

时间窗: 2 years

Number of occurrences where sedation is inadequate for treatment and number/type of rescue medication used to achieve adequate sedation

Time of Discharge

时间窗: 2 years

Time of patient discharge or transfer from Emergency Department

次要结局

  • Number of Adverse Outcomes(2 years)
  • Rate of Hospital Admission(2 years)
  • Time from Triage to initiation of procedural sedation(2 years)
  • Length of time spent in Emergency Department(2 years)
  • Duration of Procedure and Time to discharge(2 years)

研究者

发起方
Amber Graystone
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Amber Graystone

Principle Investigator

Niagara Health System

研究点 (1)

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