NL-OMON30655已完成不适用
Differential effect of adalumimab versus etanercept on apoptosis in the psoriatic skin - Adalumimab versus etanercept; apoptosis in the psoriatic skin
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. Man and woman older than 18 year en younger than 75 year
- •2. Diagnosis of Psoriatic arthritis with involvement of the peripheral joints
- •3. Failure on etanercept therapy as measured by PASI and DAS
- •4. Indication for treatment with etanercept according to the LABAG guidelines
- •5. Active disease despite treatment with methotrexate and etanercept, MTX >_ 15 mg/wk in a stable dosis during 3 months; still active skin lesions despite MTX and etanercept treatment
- •5. Corticosteroids (max 10 mg/day) en NSAID*s stable dose.
- •6. Signed informed consent.
排除标准
- •1. Rheumatoid arthritis and/or other autoimmune diseases
- •2. Pregnancy / breastfeeding.
- •3. TBC/ hepatitis b or c or other chronic infections.
- •4. Contraindications for TNF-alpha like a malignancy or a chronic demyelinating disease.
- •5. No participation in another study.
- •6. No PUVA or vitamine D treatment during 1 month before and during the study.
研究者
相似试验
招募中
3 期
comparison of the effect of Adalimumab and Infleximab in patients with Ankylosing Spondilitis presenting to Alzahra hospitalAnkylosing Spondylitis.Ankylosing spondylitisIRCT20200412047047N1Esfahan University of Medical Sciences80
招募中
不适用
Relation between Efficacy of Adalimumab and Pharmacokinetics in Ulcerative colitis.lcerative colitisJPRN-UMIN000013788Department of Medicine, Shiga University of Medical Science40
已完成
不适用
Comparison of efficacy between adalimumab 80mg every other week vs 40mg every week in Crohn's disease(WAVE-K study)s diseaseCrohn's diseaseJPRN-UMIN000023871Fukuoka University Chikushi Hospital100
已完成
不适用
Effect of adacolumn and adalimumab combination therapy for the active stage Crohn's diseases diseaseCrohn's diseaseJPRN-UMIN000007047Yamaguchi University Graduate School of Medicine Department of Gastroenterology and Hepatology40
已完成
不适用
Prospective study on the effects of adalimumab treatment in patients with rheumatoid arthritisMusculoskeletal DiseasesArthropathiesRheumatoid arthritisISRCTN68762628Academic Medical Center (AMC) (The Netherlands)50